Metabo

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Metabo Project

Technological Approach

The overall implementation strategy for the METABO platform and environment relies on the interrelated development of four main sub-projects or streamlines (SP):

• SP1–RTD1: Comprehensive monitoring. This includes the identification, adaptation and integration of existing state-of-art and beyond-state-of-art monitoring tools and equipments (sensors, medical and physical data analysis devices) not or minimally invasive, able to collect personal and ambient parameters and to elaborate them in order to provide immediate alerting in case of critical situations. Collected data are also stored and maintained for modelling and analysis.
• SP2–RTD2: Patient’s metabolic simulation and modelling. Development of data mining and data analysis tools enabling the building of metabolic process models for single patients and for categories of diabetic subjects, to predict their answers to treatments in a large spectrum of “normal life situations”. This includes the creation of an inference engine for data analysis, the development of a Clinical Decision Support System based on data and on refined modelling algorithms achieved by strict collaboration between clinicians, model experts/ mathematicians and IT specialists.
• SP3–RTD3: Personalization of healthcare processes. Based on the results of the monitoring and modelling activities and on best practice assessed by clinical guidelines and evidence-based medicine (EBM), with the aim of providing healthcare professionals with a permanent and continuous data flow and data analysis mechanisms, supporting their therapeutic decisions for each individual. This includes the identification of behavioural patterns and the implementation of simulation technologies to activate pathway actions when needed. Organizational impacts of the introduction of METABO into the care provision flows at primary and secondary care levels, in GPs surgeries, hospitals departments and dedicated centres for metabolic diseases, will be analysed to identify benefits in terms of performance, improved treatments and cost reduction for the healthcare system.
• SP4–RTD4: Integrated METABO Platform. To integrate the results of the above three research areas and make the three RTD using Representational State Transfer architecture Subprojects systems interoperate. Interoperability-related components will be developed for semantic data sharing and user interface access and harmonization and communication. This Sub-Project also includes Pilot activities, as detailed in the following, aimed at validating the overall endeavour results.